The Blues are already leading 1-0 in the quarter-final clash and have the upper hand going into the match at Stamford Bridge on Thursday evening.
Sarri makes four changes from the side that won in Prague last week.
Antonio Rudiger, Marcos Alonso, Jorginho and Willian come out of the team and are replaced by Emerson, David Luiz, N’Golo Kante and Eden Hazard.
The Chelsea manager rested some of his star players for the first leg with Kante and Hazard both coming off the bench during the second half.
Alonso scored the winner with just four minutes left to grab an all important away goal.
It would seem Sarri is taking no chances for the second leg and has picked a strong side.
There is still no starting place for Callum Hudson-Odoi, though, as he was named as a substitute.